Journal: Micromachines

Article Title: Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control

doi: 10.3390/mi13050774

Figure Lengend Snippet: The Module-Fluidic generates the desired concentration profile that enables downstream microfluidic devices’ function.

Article Snippet: All the valves are controlled by a microfluidic valve control matrix (MUX QUAKE VALVE, Elveflow) with sixteen independent pressure outlets that can provide a constant pressure input when they are switched on.

Techniques: Concentration Assay

Journal: Micromachines

Article Title: Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control

doi: 10.3390/mi13050774

Figure Lengend Snippet: Structures of the Spatio-Temporal Concentration Controller. ( A ) 3D structure of Signal generator (Oscillator) and Module Connector (Integrator), the Oscillator consists of three layers, the PDMS structure layer has flow channels patterned. The channel is molded using positive photo resist which produces a semi-cylindrical cross-section for complete sealing of the micro valve. The second layer is a thin PDMS membrane with controlling valves when the air pressure (∼20 psi) is applied, valve will seal the channel. The third layer is glass slide to support the entire structure. All layers are bounded to each other using plasma bonding. The Integrator is a single microfluidic channel with depth 25 µm. The PDMS layer is also bounded to a glass slide; ( B ) Drawings of the oscillator and integrator ( C ) Concentration signal generation achieved by combination of valve status; ( D ) Function generated by the oscillator.

Article Snippet: All the valves are controlled by a microfluidic valve control matrix (MUX QUAKE VALVE, Elveflow) with sixteen independent pressure outlets that can provide a constant pressure input when they are switched on.

Techniques: Concentration Assay, Membrane, Clinical Proteomics, Generated